Sexual Disease And Dysfunction in Men and Women Sexual dysfunction -- having a problem with sexual desire or response -- covers a wide variety of problems. In men, they include erectile dysfunction (ED) and premature or delayed ejaculation in men, and in women, spasms of the vagina and pain with sexual intercourse. For both sexes, they can include other problems with sexual desire and response. Though there are many causes of diminished libido and sexual dysfunction in men and women, there are also many ways to increase libido and rekindle the joy of sex once you identify the problem.Sexual dysfunction in women is grouped into different disorders: sexual pain, problems with desire, arousal problems, and orgasm difficulty. Changes in hormone levels, medical conditions, and other factors can contribute to low libido and other forms of sexual dysfunction in women